Curriculum Vitae
Thomas F. Lüscher, MD, FRCP
Thomas F. Lüscher https://orcid.org/0000-0002-5259-538X
| EDUCATION | |
| University degrees | |
| Habilitation | ‘Endothelial Vasoactive Substances and Cardiovascular Disease’ (equivalent to Ph.D. thesis), University of Basel, Switzerland |
| U.S. Medical (V.Q.E.) | Visa Qualifying Examination |
| Examinations | Frankfurt, Germany Certification of the Educational Commission for Foreign Medical Graduates (E.C.F.M.G.), Frankfurt, Germany |
| Doctoral thesis | «Extrarenal manifestations of fibromuscular renovascular hypertension», University of Zurich, Switzerland |
| Academic positions | |
| 2019 – present | Professor of Cardiology, King’s College, London, UK |
| 2018 – 2023 | Professor of Cardiology, Imperial College, London, UK |
| 2017 – present | Professor of Cardiology and Cardiovascular Physiology, University of Zurich, Switzerland |
| 2004 – 2017 | Professor of Cardiology and Cardiovascular Physiology, University of Zurich, Switzerland |
| 1996 – 2004 | Professor of Cardiology, University of Zurich, Switzerland |
| 1993 – 1996 | Professor of Medicine (Cardiology), University of Bern, Switzerland |
| 1992 – 1996 | Professor of Medicine (Pharmacotherapy), University of Basel, Switzerland |
| 1989 – 1992 | Assistant Professor of Medicine (Privatdozent), University of Basel, Switzerland |
| Board certifications | |
| 1989 | Swiss Board of Cardiology |
| 1987 | Swiss Board of Internal Medicine |
| 2017 | License to Practice, Cardiology, General Medical Council, United Kingdom |
| POSTGRADUATE TRAINING IN MEDICINE | |
| Training in Internal Medicine and Cardiology | Echocardiography Laboratory (Head: Dr. A.J. Tajik), Division of Cardiovascular Diseases and Internal Medicine (Chairman: Dr. H.C. Smith), Department of Medicine (Chairman: Dr. R.E. Weeks), Mayo Clinic, Rochester, MN, USA |
| Research Associate, Cardiovascular Physiology (Heads: Dr. J.T. Shepherd and Dr. P.M. Vanhoutte), Department of Physiology and Biophysics (Chairman: Dr. J. Szurszewski), Mayo Clinic and Mayo Foundation, Rochester, MN, USA | |
| Division of Cardiology (Head: Dr. H.P. Krayenbühl), Department of Internal Medicine, Medical Policlinic (Chairman: Dr. W. Siegenthaler), University Hospital Zurich, Switzerland | |
| Department of Internal Medicine (Chairman: Dr. W. Siegenthaler), University Hospital Zurich, Switzerland | |
| STAFF POSITIONS | Director of Research, Education and Development, Royal Brompton and Harefield Hospitals and Consultant Cardiologist (80%; 2017 – present) |
| Director of the Center for Molecular Cardiology, University of Zurich, Switzerland (2014 – present) | |
| Chairman of Cardiology, University Hospital Zurich, Switzerland (1996 – 2017) | |
| Vice-Chairman of Cardiology, University Hospital (Inselspital), Bern, Switzerland (1994 – 1996) | |
| Director, Clinical Pharmacology, University Hospital Basel, Switzerland (1990 – 1993) | |
| RESEARCH ACTIVITIES |
Applied Basic Research: Focus on the role of endothelium-derived mediators (i.e. nitric oxide, reactive oxygen species, prostaglandin H2, endothelin-1 and tissue factor) in the regulation of vascular tone, platelet-vessel wall interaction, coagulation (tissue factor) as well as vascular structure in physiology and in hypertension, in high LDL-cholesterol and HDL dysfunction and atherosclerosis (with a focus on LOX-1) using cellular and molecular techniques as well as ge-netically engineered animal models. More recently, aging (p66shc) and longevity genes (Sirtuins, jun-D) in wild-type and diabetic mice have been studied. |
| Clinical Research: Translation of basic findings and focus on vascular dysfunction in hyper-tension, hyperlipidemia, coronary artery disease and congestive heart failure employing ple-thysmography, ultrasound, angiography, IVUS, optical coherence tomography, positron emis-sion tomography and magnetic resonance imaging. Also, nutritional and pharmacological inter-ventions and of devices and catheter-based interventions are investigated. | |
| Registries: The natural history has and is further investigated in large registries enrolling pa-tients with acute coronary syndromes (Swiss SPUM–ACS registry; n=4’947; the AMIS-Plus registry , n =50’000, the HEART-ACS registry, Harefield Hospital, n= 600, but still recruiting,), Tako Tsubo Registry (InterTAK Registry; n=2’100; 2014- 2018). | |
|
Clinical Multicenter Trials: Translation of knowledge into clinical practice in the following trials (all published in high impact journals; see list of publications):
|
|
| Board Memberships and Reviewing of Academic Institutions | |
| 2020 | Reviewer of the Research Programmes of Charles University, Czech Republic |
| 2019 | Reviewer of the Research Programme of the University of Mainz, Germany |
| 2013 – 2019 | Chairman of the Scientific Advisory Board, Centro Nacional de Investigaciones Cardiológicas, Madrid, Spain |
| 1998 – 2015 | Chief Reviewer, Max Delbrück Center, Charité University, Berlin-Buch, Germany |
| 1999 | Chief Reviewer of the Amsterdam Academic Center, Amsterdam, The Netherlands |
| 1999 | Reviewer of the German Ministry for Research, University of Würzburg, Germany |
| 1997 | Reviewer of the British Heart Foundation Professorship at University College London, UK |
| Honorary Memberships |
|